Intended use:

For in vitro diagnostic use. RIDA®GENE Faecalibacterium prausnitzii is a multiplex real-time PCR for the direct qualitative and quantitative detection of Faecalibacterium prausnitzii DNA in human stool samples.

General information:

Faecalibacterium prausnitzii is a gram-positive, strictly anaerobic, commensal bacterium and belongs to the family of Clostridiacea. F. prausnitzii is one of the most important bacteria in the human gut flora and makes up to 5-10 % of the total number of bacteria detected in stool samples from healthy humans. F. prausnitzii localization seemed to depend upon anaerobic conditions only found in the lower gut. In early infancy the number of F. prausnitzii is very low and increases after the establishment of primocolonizing bacteria. They are strictly anaerobic and thus difficult to grow in culture. Consequently, this explains why the mechanisms of its protection potential are still poorly understood. F. prausnitzii produces butyric acid derivates e.g. butyrate, which are essential for the intestinal activity. Butyrate plays an important role for the metabolism in the colon. They serve as energy sources for the colonocytes and have anti-inflammatory effects and maintain the activity of bacterial enzymes and protects the digestive system against intestinal pathogens. Changes in the number of F. prausnitzii are an indication for dysbiosis in the human gut flora. A significant reduction of F. prausnitzii is detected by patients with diabetes and chronic inflammatory intestinal disorders (Morbus Crohn, Colitis ulcerosa, IBS). For the latter case, the intestinal barrier is disrupted or rather the intestinal wall gets more permeable. This leads to an unregulated mass exchange and causes diarrheal diseases and inflammatory reactions.

Advantages

  • Quantitative PCR results within 1 hour
  • Shelf life for 24 month after production
  • Ready-to use reagents
  • 20 Freeze/Thaw cycles
  • Harmonized workflow for RIDA®GENE Gut Balance, RIDA®GENE Akkermansia muciniphila and RIDA®GENE Faecalibacterium prausnitzii
  • Standardized PCR profile allows parallel processing of multiple RIDA®GENE assays (RNA and DNA)
  • All necessary controls included (Internal Control, Positive Control and No Template Control)
  • CE-marked

Accessories:

Specifications
Art. No. PG0155
Test format 100 reactions
Files

Dear customers,

we have started to provide the documents for our products in an electronic format. These are the Instructions for Use (IFU), the Safety Data Sheets (SDS) and the Certificate of Analysis (CoA). For batches placed on the market after 01 January 2023, you can find our documents on the eIFU portal eifu.r-biopharm.com/clinic.

Similar products
RIDA®GENE Gut Balance
RIDA®GENE Gut Balance
For in vitro diagnostic use. RIDA®GENE Gut Balance is a multiplex real-time PCR for the direct qualitative and quantitative detection of Bacteroide...
RIDA®GENE Akkermansia muciniphila
RIDA®GENE Akkermansia mucin...
For in vitro diagnostic use. RIDA®GENE Akkermansia muciniphila is a multiplex real-time PCR for the direct qualitative and quantitative detection o...
RIDA®CYCLER
RIDA®CYCLER
The RIDA®CYCLER is a magnetic induction real-time PCR cycler with 4 channels (FAM, HEX/VIC, ROX, Cy5). For research use only. Not for use in diagn...

Start typing and press Enter to search

pg0145_rida-gene-akkermansia-muciniphila