Intended use:
For in vitro diagnostic use. RIDA®GENE Gut Balance is a multiplex real-time PCR for the direct qualitative and quantitative detection of Bacteroides– and Cluster XIVa DNA from human stool samples.
General information:
90% of the normal human gut flora is populated by two phylogenetic groups which exist in a symbiotic balance. Bacteroides are anaerobic, gram-negative bacteria which are part of the normal gut flora of the intestinal tract. In the large intestine, approximately 1011 Bacteroides/g stool exist and are therefore the dominant bacteria in terms of numbers. The second phylogenetic group is the firmicutes. Clostridium Cluster XIVa are a class of firmicutes to which, besides others, Eubacterium spp. and roseburia spp. belong.
Different sources associate a disbalance of the composition of the gut flora (dysbiosis) with obesity. Here, a decreased number of Bacteroides corresponds to presence of obesity whereas at the same time an increasing number of Eubacterium rectale was detected in patients with obesity.
Art. No. | PG0105 |
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Standard range | real-time PCR with 100 reactions |
Shelf life | 24 month after production |
Sensitivity | Analytical Sensitivity : ≥ 10 DNA copies per reaction |