Intended use:

RIDASCREEN® IFX Monitoring is an enzyme linked immunoassay intended for the quantitative determination of infliximab (IFX, Remicade®, RemsimaTM, Inflectra®, anti-TNFα) in human serum and plasma.

Key features of RIDASCREEN® IFX Monitoring:

* KU Leuven (Belgium) was conducting the Taxit study which demonstrated the positive effect of therapeutic drug monitoring (TDM) of Infliximab (IFX) in regards to cost saving and therapy optimization. They are world leaders in drug monitoring..

Individual dose adjustment by measuring drug levels

Due to individual pharmacokinetics, different people show different drug levels in the blood even though they receive identical IFX dosage. However, a certain drug concentration in the patient’s blood must be present to be effective. By therapeutic drug monitoring of infliximab this can be checked and the dosage can be optimally adjusted to the needs of the patient.

For this purpose, the IFX drug concentrations in the blood are tested before the next infusion. In addition to the therapeutic benefits, TDM of infliximab helps reducing the cost of treatment.

Result TDM of infliximab Therapy optimization / action
Low bioavailability of IFX in the blood Increase dosage or decrease infusion interval
Bioavailability of IFX in the blood too high Reduction of dosage or increase infusion interval
Adequate bioavailability but lack of response of patient to the treatment Switch to alternative form of treatment

Art. No. G09041
Test format Microtiterplate with 96 wells (12 strips with 8 breakable wells each)
Standard range 6 Standards (0 / 5 / 10 / 20 / 60 / 120 ng/ml)
Incubation time approx. 2 h 10 min
Spanish (German) (English) (French) (Italian) (Spanish)
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