Intended use:

For in vitro diagnostic use. RIDA®GENE Adenovirus is a real-time PCR for the direct, qualitative detection of Adenovirus from human throat rinsing fluid, sputum and bronchoalveolar lavage fluid (BAL). The RIDA®GENE Adenovirus real-time PCR is intended for use as an aid in diagnosis of respiratory infections caused by adenoviruses.

General Information:

Adenoviruses are non-enveloped ikosaedric double-stranded DNA (dsDNA) viruses and belong to the family of Adenoviridae. They were isolated from human pharyngeal tonsils (Adenoides), where their name originated from. One differentiates 51 human pathogenic adenovirus serotypes, which can be subdivided in six groups (A – F). Adenoviruses cause a variety of different clinical pictures. Besides ocular and gastrointestinal infections, adenoviruses mostly cause respiratory disease. The latter one is primarily observed in small children under the age of four since they lack humoral immunity. However, 1 – 7% of adult respiratory infections are caused by adenoviruses. The symptoms of an adenovirus infection reach from cold, acute bronchitis to pneumonia and in immunocompromised patients, also acute respiratory distress syndrome (ARDS) is observed. Acute respiratory infections are mainly caused by sero types 1-3, 4, 6, 7, 14 and 21, whereas serotypes 1-4 and 7 are the major causes of pneumonia. Many adenoviruses are endemic with adenovirus outbreaks being often described on military bases. In 2006/2007, a new adenovirus variant of serotype 14 lead to a major respiratory disease outbreak with a mortality rate of 5%.

The clinical picture of an adenovirus infection is also dependent on its viral entry to the host. Inhalation with adenovirus 7 leads to major infection of the lower respiratory tract but oral uptake of adenovirus 7, if at all, may only lead to mild infection.

Art. No. PG1005
Test format real-time PCR with 100 reactions
Shelf life 24 months after production
English (German) (English) (French) (Italian) (Spanish)
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